1. Identify the key concepts from your question using the PICO framework.
2. List synonyms or alternative terms for each concept and organise them in a concept grid like the one below - using a column for each major concept. Tools and tips to assist with this process:
Population | Intervention | Comparator | Outcome |
3. Create your search strategy from the concepts, synonyms, phrases etc in your concept grid.
4. Use database limits to filter your search to the appropriate study type, for example in Medline and Embase on Ovid you can use the Clinical Queries filters (under Additional Limits) if it is Therapy, Diagnosis, Prognosis, or Causation - etiology, to limit your search to the appropriate study types.
Your Clinical or Faculty Librarian will be able to assist with this process.